Sex workers may operate in variety of settings such as brothels, riverbanks, bars, parks, under contraction buildings, street corners, hotels, etc. Sex work does not consider in Bangladesh, expect 14 reported brothels. Some HIV/AIDS or social workers suspected that brothel sex worker in Bangladesh is limited, near about 35,000 to 45,000, but other category sex workers is no countable, it is suspected more then 1,00,000. Dhaka city, for example, has approximately 5,000-15,000 female sex workers--an estimate (Source: Rainbow Nari O Shishu Kallyan Foundation). In most Cities, however, validated estimates of the numbers of sex workers are almost non-existent.

All estimates require regular updating and validation but these two approaches are worthy of repetition in other settings. Neither method can work without the trust and involvement of commercial sex workers themselves.

Frequency of exposure to HIV infection through sexual intercourse is the key factor for transmission of HIV among sex workers. For example, there are many countries; a significant proportion of sex workers is infected with HIV. The rates might vary from less than 1 percent to 40 percent or higher in some settings.

Even where HIV infection has not yet increase extensively, STD infection is often very high among sex workers. For example, in one brothel area in Bangladesh, 95 percent of 466 sex workers tested positive to antibodies for genital herpes virus and 60 percent for syphilis, although HIV was not detected among any of them. With the sequence of the epidemic, HIV tends to increase where other STDs are present.

There are many aspects to the nexus of drug use and HIV infection, In most of Bangladesh, people who choose to use drugs (Smoking-drug, morphia, heroin, hashish, Medicare-drug some kinds of sleeping pill, cold syrup, injections etc) that are not all socially sanctioned are treated as entirely outside society, enemies even of the social structure. The factor of Injection/ intravenous Drug Users (IDUs), which is directly can influence of HIV/AIDS, STDs/STI. For the majority of injecting drug users (IDUs), it means that lip-service is paid to the principles supposedly learned through the course of the epidemic: in relation to IDUs and the risks of HIV transmission, issues such as human rights, peer education, community participation, and legal and social change are unachievable fictions.

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